in silico

ICE, ICE, Data: Using NICEATM’s Integrated Chemical Environment to support chemical evaluations


Description

Welcome to the NURA course ICE, ICE, Data: Using NICEATM’s Integrated Chemical Environment to support chemical evaluations.


NICEATM’s Integrated Chemical Environment is a free online suite that houses curated toxicity and physicochemical property data, integrated into a variety of tools to analyze and visualize chemical data. These tools provide data access adhering to FAIR principles: data that is Findable, Accessible, Interoperable, and Reusable for chemical characterization, PBPK, IVIVE, and more!


Speakers:

Jessica Ponder, PhD, (formerly) Physicians Committee for Responsible Medicine, Moderator

Eryn Slankster-Schmierer, PhD, Physicians Committee for Responsible Medicine, Moderator

Nicole Kleinstreuer, PhD, NICEATM Director

Jaleh Abedini, MSc Senior Data Analyst, NICEATM

Bethany Cook, Msc, Senior Computational Chemist, NICEATM

Agnes Karmaus, Senior Toxicologist, (formerly) Inotiv

David Hines, PhD, is a Computational Toxicologist, NICEATM

Xiaoqing Chang, PhD, Senior Computational Toxicologist at Inotiv-RTP


This course was recorded in April 2022. Credentials and affiliations for speakers and presenters may have changed since the recording.


The videos in this course are available with English and Spanish subtitles. To access these, select the "Settings" (gear) icon within the video.

Content
  • Section 1 Introduction
  • 1.1 Introduction and Overview of the Integrated Chemical Environment
  • 1.2 Search Tool and Data Query
  • 1.3 Chemical Quest and Chemical Characterization
  • Section 1 Q&A
  • Section 2 Introduction
  • 2.1 cHTS Data and Curve Surfer
  • 2.2 Physiologically Base Pharmacokinetic (PBPK) Modeling
  • 2.3 In Vitro In Vivo Extrapolation (IVIVE) Modeling
  • Section 2 Q&A
  • Course Survey
Completion rules
  • All units must be completed
  • Leads to a certificate with a duration: Forever